The autosomal recessive form of the Hyper IgE syndrome (AR-HIES) with dedicator of cytokinesis 8 (DOCK8) deficiency is associated with difficult to treat persistent viral skin infections including papilloma virus infection. 2b therapy maybe useful in controlling recalcitrant viral infections in these patients. gene identified a homozygous mutation in intervening sequence (IVS) 40 splice donor… Continue reading The autosomal recessive form of the Hyper IgE syndrome (AR-HIES) with