These findings highlight the need for the IgG subclass change to IgG4 for the anti-PLA2R antibodies to become pathogenic. 1:274, P < 0.001). IgG2(45.1%) was predominant in organic antibodies, while IgG4 was predominant in Ab + group (45.7 vs. 25.0%,P< 0.001). IgG1 was raising from organic antibodies to Ab- and Ab + organizations. The affinity… Continue reading These findings highlight the need for the IgG subclass change to IgG4 for the anti-PLA2R antibodies to become pathogenic