Its existence was confirmed by further function in mice (35, 36), and direct proof its involvement in the delivery of maternal IgG originated from perfused placenta research looking at the maternofetal transfer of the recombinant IgG1 with this of a version containing a mutation in the Fc area that didn’t bind to FcRn (37). The… Continue reading Its existence was confirmed by further function in mice (35, 36), and direct proof its involvement in the delivery of maternal IgG originated from perfused placenta research looking at the maternofetal transfer of the recombinant IgG1 with this of a version containing a mutation in the Fc area that didn’t bind to FcRn (37)