The production of functional elements is an important regulatory mechanism for RNA viruses. In the life cycle of SARS-CoV-2, ORF 1?ab encodes two long overlapping polyproteins, pp1a and pp1ab, which can be processed into 16 nonstructural proteins (nsps) required for RNA transcription and genome replication [16,25] (Fig.?1 ). classified into animal and human CoVs according… Continue reading The production of functional elements is an important regulatory mechanism for RNA viruses
Month: October 2022
This group can be substituted with some other group which is capable of h-bond donation
This group can be substituted with some other group which is capable of h-bond donation. 4. held with Zolinza, the recently FDA authorized drug as potent histone deacetylase inhibitor. Our model consists of 5 features: Hydrogen relationship donors, Hydrogen relationship acceptors, H-bond donor/acceptors, Aromatic ring centers, and hydrophobic centers. With the aid of this pharmacophore… Continue reading This group can be substituted with some other group which is capable of h-bond donation