Soma location, dendrite morphology, and synaptic innervation may represent key determinants of functional responses of individual neurons, such as sensory-evoked spiking. spine distribution of neuron to the total spine distribution of all neurons in the column, to the bouton distribution of presynaptic cell type and denotes MSH6 a term to correct for missing neuron populations… Continue reading Soma location, dendrite morphology, and synaptic innervation may represent key determinants
Tag: CAY10505
The β-site amyloid precursor protein (APP)-cleaving enzyme 1 (β-secretase BACE1) initiates
The β-site amyloid precursor protein (APP)-cleaving enzyme 1 (β-secretase BACE1) initiates amyloidogenic processing of APP to generate amyloid β (Aβ) which is a hallmark of Alzheimer disease (AD) pathology. whereas the RNAi knockdown of endogenous Rheb promotes BACE1 accumulation and this effect by Rheb is independent of its mTOR signaling. Moreover GTP-bound Rheb interacts with… Continue reading The β-site amyloid precursor protein (APP)-cleaving enzyme 1 (β-secretase BACE1) initiates