Background Osteoarthritis (OA) is a degenerative osteo-arthritis characterised by cartilage degradation and chondrocyte hypertrophy. an OA model was made by anterior cruciate ligament transection in mice. CA-Rac1 GFP and DN-Rac1 lentivirus or NSC23766 were injected intra-articularly. Joints were put through histological analysis. Outcomes It was discovered that there is certainly aberrant Rac1 activation in individual… Continue reading Background Osteoarthritis (OA) is a degenerative osteo-arthritis characterised by cartilage degradation