Previous studies out of this laboratory have confirmed a crucial role of cytosolic phospholipase A2 (cPLA2) and arachidonic acid solution in angiotensin II (Ang II) AT2 receptor-mediated sign transduction in renal epithelium. appears that p38SAPK is certainly upstream of ERK1/2 and Akt1, since a p38SAPK inhibitor SB203580 considerably obstructed H2O2-induced activation of ERK1/2 and Akt1.… Continue reading Previous studies out of this laboratory have confirmed a crucial role