The introduction of novel therapeutic agents is vital for combating the

The introduction of novel therapeutic agents is vital for combating the increasing number of instances of dengue fever in endemic countries and among a lot of travelers from non-endemic countries. ~370 kDa polyprotein precursor comprising the structural proteins C, prM, and E and seven nonstructural proteins referred to as NS1, NS2A, NS2B, NS3, NS4A, NS4B… Continue reading The introduction of novel therapeutic agents is vital for combating the

Peripheral corticotropin-releasing hormone (CRH) can be an important regulator of localized

Peripheral corticotropin-releasing hormone (CRH) can be an important regulator of localized inflammatory responses. receptor NR4A2 through the reconstitution of cAMP/protein kinase A/cAMP response element-binding protein signaling and identified a role for CRH in modulating nuclear factor B transcriptional activity. CRH enhanced the expression of nitric-oxide synthase (NOS III) to promote NO production from CRH-R1-expressing cells.… Continue reading Peripheral corticotropin-releasing hormone (CRH) can be an important regulator of localized