Prolyl oligopeptidase (PREP) inhibition by small-molecule inhibitors may reduce alpha-synuclein (aSyn) aggregation, an integral participant in Parkinsons disease pathology. response to aSyn, while cells had been restored to wild-type cell amounts after PREP overexpression. Used collectively, our data shows that PREP can boost aSyn toxicity (SN) of wt and PREPko mice, we’ve measured Mubritinib behavioral… Continue reading Prolyl oligopeptidase (PREP) inhibition by small-molecule inhibitors may reduce alpha-synuclein (aSyn)