Open in another window A series of novel benzene- and 2,3,5,6-tetrafluorobenzenesulfonamide was synthesized with a click chemistry strategy beginning with azido-substituted sulfonamides and alkynes, incorporating aryl, alkyl, cycloalkyl, and amino-/hydroxy-/halogenoalkyl moieties. which once again had excellent inhibitory activity against the tumor-associated isoforms CA IX and XII.7 Among click methods, the copper-catalyzed azideCalkyne cycloaddictions (CuAAC) possess… Continue reading Open in another window A series of novel benzene- and 2,3,5,6-tetrafluorobenzenesulfonamide