Supplementary Materials Supporting Figures pnas_0608017103_index. revealed by bioluminescence imaging. Histological Tideglusib inhibitor examination revealed that upon MYC inactivation, the loss of p53 led to a insufficiency in thrombospondin-1 (TSP-1) manifestation, a powerful antiangiogenic proteins, and the next inability to shut down CD1B angiogenesis. Repair of p53 manifestation in these tumors re-established TSP-1 manifestation. This allowed… Continue reading Supplementary Materials Supporting Figures pnas_0608017103_index. revealed by bioluminescence imaging. Histological