Appropriate fix of DNA lesions as well as the inhibition of DNA fix activities at telomeres are important to avoid genomic instability. recombination (CSR). These actions of MAD2L2 rely on ATM kinase activity, RNF8, RNF168, 53BP1 and RIF1, however, not on PTIP, REV3 and REV1, the last mentioned two performing with MAD2L2 in translesion synthesis… Continue reading Appropriate fix of DNA lesions as well as the inhibition of