Temporal and spatial control of transcription in development is usually dictated to a great extent by transcriptional repressors. its own promoter, establishing a feedback loop (Fischer and Gessler, 2007). This opinions loop can induce oscillations in Hes1 protein levels (Kageyama et al., 2007). Periodic temporal expression of Hes1 plays a crucial role in formation of… Continue reading Temporal and spatial control of transcription in development is usually dictated