TGR5 is really a G protein-coupled receptor that mediates bile acid (BA) effects on energy balance inflammation digestion and sensation. TGR5 endocytosis or recruitment of β-arrestins as assessed by confocal microscopy. DCA taurolithocholic acid and oleanolic acid did not stimulate TGR5 association with β-arrestin 1/2 or G protein-coupled receptor kinase (GRK) 2/5/6 as determined by… Continue reading TGR5 is really a G protein-coupled receptor that mediates bile acid