Latent infection of B lymphocytes by Epstein-Barr trojan (EBV) results in their immortalization into lymphoblastoid cell lines (LCLs); this latency system is controlled from the EBNA2 viral transcriptional activator which focuses on promoters via RBPJ a DNA binding protein in the Notch signaling pathway. binding at sites near EBNA3A- or EBNA3C-regulated genes is definitely specifically… Continue reading Latent infection of B lymphocytes by Epstein-Barr trojan (EBV) results in