The transcriptional coactivator has been identified as a gene SCH-527123 overexpressed in certain types of human acute myeloid leukemia. balanced t(4;22) in a patient with meningioma. Therefore the gene was thought to be a candidate for the meningioma tumor suppressor gene on chromosome 22[1] although its relation to meningioma remains unresolved. The encoded protein of… Continue reading The transcriptional coactivator has been identified as a gene SCH-527123