Supplementary MaterialsSupplementary Information srep39121-s1. by hyperaldosteronism, impacts 20% of individuals with

Supplementary MaterialsSupplementary Information srep39121-s1. by hyperaldosteronism, impacts 20% of individuals with resistant hypertension1. Somatic mutations in the selectivity filter of the potassium channel, GIRK4 (encoded by and gene transcription and an increase in aldosterone biosynthesis2. (-catenin) mutations have been reported in APAs6 and in cortisol-secreting RTA 402 pontent inhibitor or non-functional adenomas7. Constitutive activation of… Continue reading Supplementary MaterialsSupplementary Information srep39121-s1. by hyperaldosteronism, impacts 20% of individuals with