Osteoarthritis (OA) may be the most common joint disease affecting close to 27 million Americans. postnatal long bone development. Interestingly, histological analysis detected less articular cartilage absorption, while immunohistochemistry assay detected upregulated Sox9 expression in mouse joints compared to controls, implying that delayed chondrocyte hypertrophy may be OA protective. Indeed, we have performed Tgf-1 injection… Continue reading Osteoarthritis (OA) may be the most common joint disease affecting close