Cisplatin level of resistance is a major problem affecting ovarian carcinoma treatment. siRNA enhanced cisplatin-induced cell death in Rabbit Polyclonal to Neuro D A2780cp cells, suggesting that inhibition of autophagy renders resistant cells to become more sensitive to cisplatin. Taken collectively, Nrf2 signaling may regulate cisplatin resistance by activating autophagy. Findings: Nrf2-triggered autophagy may function… Continue reading Cisplatin level of resistance is a major problem affecting ovarian carcinoma