Post-natal proliferation of cerebellar granule neuron precursors (CGNPs) proposed cells-of-origin for the SHH-associated subgroup of medulloblastoma (MB) is normally motivated by Sonic Hedgehog (Shh) and Insulin-like Growth Factor (IGF) in the growing cerebellum. the Shh-subgroup of MB in mice we display for the very first time that YB-1 is normally induced by Shh in CGNPs.… Continue reading Post-natal proliferation of cerebellar granule neuron precursors (CGNPs) proposed cells-of-origin for