Cribriform morular variant of PTC (CMV-PTC) frequently shows activation of the CTNNB1/Wnt pathway with nuclear build up of beta catenin. LEF-1 staining at 2+ intensity. LEF-1 experienced a level of sensitivity of 86% and specificity of 98% for the medical diagnosis of CMV-PTC. LEF-1 is normally delicate and particular marker for CMV-PTC extremely, when found… Continue reading Cribriform morular variant of PTC (CMV-PTC) frequently shows activation of the