Compounds acting via the GPCR neurotensin receptor type 2 (NTS2) display analgesic effects in relevant animal models. adverse effect profile that includes constipation respiratory depression as well as development of tolerance and addiction. Also patients experiencing chronic pain a persistent pain that can follow from peripheral nerve injury often fail to find relief with opioids.… Continue reading Compounds acting via the GPCR neurotensin receptor type 2 (NTS2) display