The core 1 1-3-galactosyltransferase (T-synthase) transfers Gal from UDP-Gal to GalNAc1-Ser/Thr (Tn antigen) to create the core 1 O-glycan Gal1-3GalNAc1-Ser/Thr (T antigen). was used to delete (Fig. 1, BCD). on both alleles caused embryonic lethality, we analyzed 293 embryos at embryonic days 9C16 (E9C16) from timed matings of encodes all T-synthase activity, at least through… Continue reading The core 1 1-3-galactosyltransferase (T-synthase) transfers Gal from UDP-Gal to GalNAc1-Ser/Thr