APOBEC-catalyzed cytosine-to-uracil deamination of single-stranded (ss)DNA has helpful functions in immunity and harmful roles in cancer. amounts of energetic polynucleotide cytosine deaminase enzymes collectively known as APOBECs1,2. All vertebrate varieties possess activation-induced deaminase (Help), which is vital for antibody gene diversification through somatic hypermutation and course change recombination3,4. Many vertebrates likewise have APOBEC1, which edits… Continue reading APOBEC-catalyzed cytosine-to-uracil deamination of single-stranded (ss)DNA has helpful functions in immunity