The administration of hormone-refractory prostate cancer represents a major challenge in the therapy of this tumor and identification of novel androgen receptor antagonists is needed to render treatment more effective. blot. experiments were performed on SCID mice xenografted with cells with different sensitivity to hormonal treatment. In hormone-sensitive LNCaP and LNCaP-AR cells the latter expressing… Continue reading The administration of hormone-refractory prostate cancer represents a major challenge in