Interleukin (IL)-27, a member of IL-12/IL-23 heterodimeric family of cytokines, has pleiotropic properties that can enhance or limit immune responses. by activating the STAT1-mediated T-box expressed in T cells (T-bet) pathway [2]. In relation to CD4+CD25+ regulatory T cell (Treg), which characteristically express the transcription factor forkhead box protein p3 (Foxp3), Cox reported that IL-27… Continue reading Interleukin (IL)-27, a member of IL-12/IL-23 heterodimeric family of cytokines, has