HIV-1 replication is certainly induced by the excess of iron and iron chelation by desferrioxamine (DFO) inhibits viral replication by reducing proliferation of infected cells. at concentrations that inhibited HIV-1 transcription. The chelators decreased cellular activity of CDK2 and reduced HIV-1 Tat phosphorylation by CDK2. The ICL670 and 311 did not decrease CDK9 protein level… Continue reading HIV-1 replication is certainly induced by the excess of iron and