By sequentially applying sonic hedgehog (C25II) and CHIR99021 (GSK3β inhibitor) to induce the midbrain ground dish progenitors and fibroblast development aspect 8 (FGF8) to market dopaminergic differentiation within a chemically defined moderate we’ve established a sturdy program for generation of midbrain dopamine (DA) neurons from individual and rhesus monkey embryonic stem cells (ESCs) and induced… Continue reading By sequentially applying sonic hedgehog (C25II) and CHIR99021 (GSK3β inhibitor) to