In H295R human adrenocortical cells ACTH rapidly activates ceramide (Cer) and sphingosine (SPH) turnover having a concomitant upsurge in SPH-1-phosphate secretion. a job because of this enzyme in glucocorticoid creation. Here the part of ASAH1 in regulating steroidogenic capability was examined utilizing a tetracycline-inducible ASAH1 brief hairpin RNA H295R human being adrenocortical steady cell range.… Continue reading In H295R human adrenocortical cells ACTH rapidly activates ceramide (Cer) and