Although RNA interference (RNAi) is a popular technique, no method for simultaneous silencing of multiple targets by small-hairpin RNA (shRNA)-expressing RNAi vectors has yet been established. to tumor development. Various genetic and epigenetic alterations of the components of the TGF-CSmad pathway have been identified in several human cancers (2C4). Although synthetic small-interfering RNA (siRNA) duplexes… Continue reading Although RNA interference (RNAi) is a popular technique, no method for