Compact disc5+ (B-1a) B cells play pivotal roles in autoimmunity all the way through expression of autoreactive B-cell receptors and production of autoantibodies. of autoantigens which autoreactive B-1a cells are chosen and extended by DS positively?autoantigen complexes. This mechanism may also explain the clonal expansion of B-1a cells using B-cell malignancies. B cells make a… Continue reading Compact disc5+ (B-1a) B cells play pivotal roles in autoimmunity all