Chronic ethanol consumption disrupts G protein-dependent signaling pathways in rat adipocytes. cAMP focus in adipocytes FXV 673 did not differ between pair- and ethanol-fed rats. The suppression in cAMP accumulation caused by ethanol feeding was associated with increased activity of phosphodiesterase 4. Chronic ethanol feeding also decreased β-adrenergic receptor-stimulated protein kinase A activation and phosphorylation… Continue reading Chronic ethanol consumption disrupts G protein-dependent signaling pathways in rat adipocytes.