Supplementary MaterialsSupplementary 41598_2018_38353_MOESM1_ESM. interaction that’s essential for protein import across the

Supplementary MaterialsSupplementary 41598_2018_38353_MOESM1_ESM. interaction that’s essential for protein import across the mitochondrial inner membrane. In order to gain deeper insight into the molecular function of Tim50, we used random mutagenesis to determine residues that are important Linifanib pontent inhibitor for its function. The temperature-sensitive mutants isolated were defective in import of TIM23-dependent precursor proteins. The… Continue reading Supplementary MaterialsSupplementary 41598_2018_38353_MOESM1_ESM. interaction that’s essential for protein import across the

Maintenance of genome integrity is crucial for proper cell growth. inter-species

Maintenance of genome integrity is crucial for proper cell growth. inter-species subunit interactions. Substitution of yeast Rfa2 with domains/regions of human Rpa2 important for Rpa2 function (and on specific residues by multiple kinases during DNA replication and in response to specific DNA damaging brokers. While some of these targets are consensus sequences (S/TQ) for phosphatidylinositol-3… Continue reading Maintenance of genome integrity is crucial for proper cell growth. inter-species