Although p53 transcriptional activation potential is critical for its ability to

Although p53 transcriptional activation potential is critical for its ability to suppress cancer, the specific target genes involved in tumor suppression remain unclear. individual survival. SIVA functions independently of p53, and instead, stimulates mTOR signaling and metabolism in NSCLC cells. Thus, SIVA enables tumorigenesis in a p53-impartial manner, exposing a potential new cancer therapy target.… Continue reading Although p53 transcriptional activation potential is critical for its ability to