Y1 receptor (Y1R)-signalling pathway plays a pivotal role in the regulation of bone metabolism. tool (BonePit), showed that Y1R?/? resorption pits displayed a marked reduction in surface area, volume and depth. Together, these data demonstrates that the lack of Y1Rs stimulates the formation of larger multinucleated osteoclasts with reduced bone-resorbing activity, unveiling a novel therapeutic… Continue reading Y1 receptor (Y1R)-signalling pathway plays a pivotal role in the regulation