Transient receptor potential (TRP) channels contribute to the regulation of intracellular calcium, which can promote cancer hallmarks in cases of dysregulation of gene transcription and calcium-dependent pro-proliferative or anti-apoptotic mechanisms. its ligand capsaicin was associated with the growth inhibition of some cancer cell types; however, the signaling components involved are complex. In this study, stimulation… Continue reading Transient receptor potential (TRP) channels contribute to the regulation of intracellular
Tag: Colec11
Purpose The vesicular acetylcholine transporter (VAChT) is a specific biomarker for
Purpose The vesicular acetylcholine transporter (VAChT) is a specific biomarker for imaging presynaptic cholinergic neurons. each tracer was completed in 55-60 min. Conclusions Two potent enantiopure VAChT ligands were synthesized and 11C-labeled with good radiochemical yield and specific activity. and study changes in MDL 28170 cholinergic function in response to therapy. Until recently only one… Continue reading Purpose The vesicular acetylcholine transporter (VAChT) is a specific biomarker for