MuRF1 is a previously reported ubiquitin-ligase within striated muscle Cladribine that targets troponin I and myosin heavy chain for degradation. increased alpha-MHC driven MuRF1 expression. Increased MuRF1 expression in and experiments revealed no alterations in the respiratory chain complex I and II function. Working perfusion experiments on MuRF1 transgenic hearts confirmed significant adjustments in blood… Continue reading MuRF1 is a previously reported ubiquitin-ligase within striated muscle Cladribine that