Primary ovarian insufficiency (POI) resulting from ovarian autoimmunity is usually a poorly understood YIL 781 clinical condition lacking in effective treatments. tolerance. We utilized a well-characterized murine model of ovarian autoimmunity whereby oophoritis develops after d 3 neonatal thymectomy (NTx). Wild-type and transgenic mice carrying an MHC Class II-driven gene (transgene had significant reductions in… Continue reading Primary ovarian insufficiency (POI) resulting from ovarian autoimmunity is usually a