Subtype-specific neurons obtained from adult humans will be critical to modeling neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). to form NMJs. A chemical screen revealed that the degenerative features of ALS-hiMNs can be remarkably rescued by the small molecule kenpaullone. Taken together our results define a direct and efficient strategy to obtain disease-relevant neuronal… Continue reading Subtype-specific neurons obtained from adult humans will be critical to modeling