Kit is a receptor-type tyrosine kinase found on the plasma membrane. endolysosomes. It resists damage because it is definitely under-ubiquitinated. Kit(D814Y) also appears in the endoplasmic reticulum soon after biosynthesis and there can activate STAT5 aberrantly. These mechanisms of oncogenic signalling will also be seen in rat and human being mast cell leukemia cells. Thus… Continue reading Kit is a receptor-type tyrosine kinase found on the plasma membrane.