The role of Forkhead Box F1 (FoxF1) transcription factor in carcinogenesis

The role of Forkhead Box F1 (FoxF1) transcription factor in carcinogenesis is not well characterized. and improved protein levels of the CDK inhibitors, p21Cip1 and p27Kip1. Depletion of both FoxF1 and FoxF2 in tumor cells completely abrogated RMS tumor growth in mice. Overexpression of either FoxF1 or FoxF2 in tumor cells was adequate to increase… Continue reading The role of Forkhead Box F1 (FoxF1) transcription factor in carcinogenesis