Tag: WBP4

Background FLT3 mutations (FLT3/Mut) are widespread in de novo AML and

Background FLT3 mutations (FLT3/Mut) are widespread in de novo AML and so are connected with early relapse. (p=0.009). In sufferers who received ATRA (C9710 or CCG-2911, n=58), people that have FLT3/Mut got an induction death count of 30% (7/23) in comparison to 3% (1/35) in FLT3/WT individuals (p=0.005). In individuals with high WBC matters (… Continue reading Background FLT3 mutations (FLT3/Mut) are widespread in de novo AML and

We describe the synthesis and properties of five dinucleotide fluorescent cap

We describe the synthesis and properties of five dinucleotide fluorescent cap analogues labelled in the ribose of the 7-methylguanosine moiety with either anthraniloyl (Ant) or N-methylanthraniloyl (Mant) which have been designed for the preparation of fluorescent mRNAs transcription a triphosphate linkage m7GpppGpNp(Np)n1 2 The unusual chemical structure of the cap is pivotal for essentially all… Continue reading We describe the synthesis and properties of five dinucleotide fluorescent cap