Pharmacological cyclin-dependent kinase (cdk) inhibitors (PCIs) block replication of many viruses

Pharmacological cyclin-dependent kinase (cdk) inhibitors (PCIs) block replication of many viruses including herpes virus type 1 (HSV-1) and individual immunodeficiency virus type 1 (HIV-1). HIV-1 replication by targeting viral or cellular protein. P-PCIs inhibited replication of HSV-1 and -2 and HIV-1 which need mobile cdks to reproduce however not vaccinia trojan or lymphocytic choriomeningitis trojan… Continue reading Pharmacological cyclin-dependent kinase (cdk) inhibitors (PCIs) block replication of many viruses

Still left ventricular (LV) hypertrophy (LVH) and congestive heart failure are

Still left ventricular (LV) hypertrophy (LVH) and congestive heart failure are accompanied by changes in myocardial ATP metabolism. (ejection fraction and systolic thickening fraction) declined significantly accompanied by deferent levels of pericardial effusion and wall stress increased in aorta banded animals at after AOB suggesting acute heart failure which recovered by when concentric LVH restored… Continue reading Still left ventricular (LV) hypertrophy (LVH) and congestive heart failure are