Supplementary MaterialsSupplementary Information 41467_2018_3224_MOESM1_ESM. Mutp53-reprogammed TAMs favor anti-inflammatory immunosuppression with increased activity of TGF-. These findings, associated with poor survival in colon cancer patients, strongly support a microenvironmental GOF role for mutp53 in actively engaging the immune system to promote cancer progression and metastasis. Introduction Exosomes are small spherical packages and one of the vesicle… Continue reading Supplementary MaterialsSupplementary Information 41467_2018_3224_MOESM1_ESM. Mutp53-reprogammed TAMs favor anti-inflammatory immunosuppression with increased