Wnt-β-catenin-T Cell Factor signaling is causally linked to c-myc dependent tumorigenesis

Wnt-β-catenin-T Cell Factor signaling is causally linked to c-myc dependent tumorigenesis in mouse and human colon epithelial cells. of thymocytes and PTC-209 intestinal epithelial cells is usually a direct consequence of the gene expression elicited by β-catenin expression in each tissue. We find that whereas intestinal cells induce genes that promote proliferation thymocytes induce expression… Continue reading Wnt-β-catenin-T Cell Factor signaling is causally linked to c-myc dependent tumorigenesis