Background Breast cancer tumor is considered to arise in mammary epithelial stem cells. but grew as regular differentiated epithelial clones when cultured. Transplantation of murine SP cells in limiting dilution into cleared mammary body fat pads generated epithelial lobuloalveolar and ductal buildings. Bottom line These data demonstrate the lifetime of an undifferentiated SP in murine… Continue reading Background Breast cancer tumor is considered to arise in mammary epithelial