Provided strong evidence implicating an important role of altered microRNA expression

Provided strong evidence implicating an important role of altered microRNA expression in cancer initiation and progression, the genes responsible for microRNA biogenesis may also play a role in tumorigenesis. combined high/middle tertiles of methylation index were associated with reduced risk of breast cancer (OR=0.34, 95% CI:0.15-0.81 and OR=0.47, 95% CI:0.24-0.94, respectively; Ptrend=0.015). These results were… Continue reading Provided strong evidence implicating an important role of altered microRNA expression

DNA double-strand breaks (DSBs), which are formed with the Spo11 proteins,

DNA double-strand breaks (DSBs), which are formed with the Spo11 proteins, start meiotic recombination. and then separate together, developing haploid gametes (sperm and eggs, in pets). Recombination, which swaps DNA between chromosomes, is crucial for chromosome parting and pairing, and promotes hereditary variety within the next era also, offering the feedstock for advancement. DNA double-strand… Continue reading DNA double-strand breaks (DSBs), which are formed with the Spo11 proteins,