Microtubule inhibitors such as for example Vinblastine and Paclitaxel are chemotherapy real estate agents that activate the mitotic spindle checkpoint, arresting cells in mitosis and resulting in cell loss of life. The spindle checkpoint causes expanded mitotic arrest. Cell loss of life ensues either through the mitotic arrest or after cells leave mitosis without regular… Continue reading Microtubule inhibitors such as for example Vinblastine and Paclitaxel are chemotherapy