DNA double-strand breaks (DSBs) are critical lesions that may lead to

DNA double-strand breaks (DSBs) are critical lesions that may lead to cell death or chromosomal rearrangements. was reduced by two orders of magnitude [9]. Also, in studies of compared to cells [10]. Other known pathways of HR DSB repair are less conservative than GC, as they cause significant change to the repaired molecule. One such… Continue reading DNA double-strand breaks (DSBs) are critical lesions that may lead to

Background Current vaccines against HPVs are constituted of L1 protein self-assembled

Background Current vaccines against HPVs are constituted of L1 protein self-assembled into virus-like particles (VLPs) plus they have been proven to protect against organic HPV16 and HPV18 infections and connected lesions. immunized with L1/L2 VLPs, and the best degrees of cross-neutralizing antibodies had been seen in mice immunized with HPV 58 L1/L2 pseudovirions encoding the… Continue reading Background Current vaccines against HPVs are constituted of L1 protein self-assembled

Background Current HIV-1 envelope glycoprotein (Env) vaccines are unable to induce

Background Current HIV-1 envelope glycoprotein (Env) vaccines are unable to induce cross-reactive neutralizing antibodies. coincided with CrNA development. These included a statistically shorter variable region 1 and a lower probability of glycosylation as implied by a high ratio of NXS NXT glycosylation motifs. Furthermore lesser probability of glycosylation at position 332 which is usually involved… Continue reading Background Current HIV-1 envelope glycoprotein (Env) vaccines are unable to induce