Three-dimensional organotypic culture using reconstituted basement membrane matrix Matrigel (rBM 3-D) is usually an indispensable tool to characterize morphogenesis of mammary epithelial cells and to elucidate the tumor-modulating actions of extracellular matrix (ECM). cells in rBM 3-Deb culture. Overexpression of the differentially expressed miR-200 family member miR429 in MDA-MB231 cells attenuated their invasive stellate morphogenesis… Continue reading Three-dimensional organotypic culture using reconstituted basement membrane matrix Matrigel (rBM 3-D)